Hypertension, Myocardial infarction, Heart, Angiotensin, Renin-angiotensin system, Angiotensin-converting enzyme

Meet ACE2, the Enzyme at the Center of the Covid-19 Mystery

On Jun 1, 2020
@WIRED shared
During the first chaotic months of the pandemic, it was already clear that Covid-19 didn’t affect everyone equally. Since January, scientists have published more than 700 studies to figure out the link between the ACE2 enzyme and the virus. https://t.co/y76rko9Jai
Open

Since January, scientists have published more than 700 studies to figure out the molecule’s link to risk for the disease—and to find possible treatments.

www.wired.com
On Jun 1, 2020
@WIRED shared
During the first chaotic months of the pandemic, it was already clear that Covid-19 didn’t affect everyone equally. Since January, scientists have published more than 700 studies to figure out the link between the ACE2 enzyme and the virus. https://t.co/y76rko9Jai
Open

Meet ACE2, the Enzyme at the Center of the Covid-19 Mystery

Meet ACE2, the Enzyme at the Center of the Covid-19 Mystery

Since January, scientists have published more than 700 studies to figure out the molecule’s link to risk for the disease—and to find possible treatments.

Smokers have more ACE2 receptors making it easier for SARS-CoV-2 to infect

Smokers have more ACE2 receptors making it easier for SARS-CoV-2 to infect

A new study published in the European Respiratory Journal in April 2020 reveals that people with smoking-damaged lungs and those with chronic obstructive pulmonary disease (COPD) are likely ...

Blood Pressure Meds Point the Way to Possible COVID-19 Treatment

Blood Pressure Meds Point the Way to Possible COVID-19 Treatment

There is little evidence that antihypertensive drugs worsen COVID-19, and scientists are instead exploring the idea that such medications—or their downstream effects—may actually alleviate ...

Men's blood contains greater concentrations of enzyme that helps COVID-19 infect cells

Men's blood contains greater concentrations of enzyme that helps COVID-19 infect cells

Evidence from a large study of several thousand patients in 11 European countries shows that men have higher concentrations of angiotensin-converting enzyme 2 (ACE2) in their blood than ...

EMA advises continued use of medicines for hypertension, heart or kidney disease during COVID-19 pandemic

EMA advises continued use of medicines for hypertension, heart or kidney disease during COVID-19 pandemic

EMA advises continued use of medicines for hypertension, heart or kidney disease during COVID-19 pandemic

Safety of ACEIs and ARBs in Patients With COVID-19—What Is the Evidence?

Safety of ACEIs and ARBs in Patients With COVID-19—What Is the Evidence?

This Viewpoint reviews the pathophysiological and observational basis for speculating that angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs) might ...

Drugs for high blood pressure don’t appear to make COVID-19 worse

Drugs for high blood pressure don’t appear to make COVID-19 worse

Drugs commonly used to treat hypertension did not lead to more severe cases of the coronavirus infection or higher mortality in hospitalized patients.

HFSA/ACC/AHA Statement Addresses Concerns Re: Using RAAS Antagonists in COVID-19

HFSA/ACC/AHA Statement Addresses Concerns Re: Using RAAS Antagonists in COVID-19

In a few experimental studies with animal models, both angiotensin converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs) have been shown to upregulate ACE2 expression ...

Weekend reading: research on coronavirus and food

Weekend reading: research on coronavirus and food

Research on this virus (officially SARS CoV-2, commonly COVID-19) is pouring out and filling every medical journal I typically read.  Here are a few recent articles on food-related aspects ...

Lessons from SARS: control of acute lung failure by the SARS receptor ACE2

Lessons from SARS: control of acute lung failure by the SARS receptor ACE2

Angiotensin-converting enzyme 2 (ACE2), a second angiotensin-converting enzyme (ACE), regulates the renin–angiotensin system by counterbalancing ACE activity. Accumulating evidence in ...

Bringing Needed Structure to COVID-19 Drug Development

Bringing Needed Structure to COVID-19 Drug Development

With so much information swirling around these days about the coronavirus disease 2019 (COVID-19) pandemic, it would be easy to miss one of the most Interesting and significant basic ...

Renin–Angiotensin–Aldosterone System Inhibitors in Patients with Covid-19

Renin–Angiotensin–Aldosterone System Inhibitors in Patients with Covid-19

Special Report from The New England Journal of Medicine — Renin–Angiotensin–Aldosterone System Inhibitors in Patients with Covid-19

Hypertension Drugs Appear Safe in COVID-19

Hypertension Drugs Appear Safe in COVID-19

Three large observational studies add to support for continued use

Coronavirus and High Blood Pressure: What’s the Link?

Coronavirus and High Blood Pressure: What’s the Link?

People with high blood pressure may get sicker if infected with coronavirus. How does it affect those with high blood pressure and how can you protect yourself? FInd out here.

Men have high levels of enzyme key to COVID-19 infection, study finds

Men have high levels of enzyme key to COVID-19 infection, study finds

Men's blood has higher levels than women's of a key enzyme used by the new coronavirus to infect cells, the results of a big European study showed on Monday -- a finding which may help ...

ACE inhibitors and angiotensin receptor blockers may increase the risk of severe COVID-19, paper suggests

ACE inhibitors and angiotensin receptor blockers may increase the risk of severe COVID-19, paper suggests

A possible explanation for the severe lung complications being seen in some people diagnosed with COVID-19 is proposed in a new article.

Treatments for COVID-19: Drugs being tested against the coronavirus

Treatments for COVID-19: Drugs being tested against the coronavirus

Here, we take a look at several of the treatments that doctors hope will help fight COVID-19, the disease caused by the novel coronavirus.