#CRISPR #pharma
Organism, Gene, DNA, Genetics, Biotechnology, Protein

Casting aside CRISPR scissors and making a point with base editors

On Feb 3, 2021
@pharmaphorum shared
CRISPR-Cas9 gene editing technology is part of a growing list of new drug applications for cell therapy treatments. Dr Jennifer Harbottle explores how the field is moving forward #pharma #CRISPR https://t.co/qVlqSwMIZb
Open

Dr Jennifer Harbottle, senior scientist in the R&D Base Editing team of PerkinElmer’s Horizon Discovery business looks at progress made in CRISPR-Cas9 gene editing.

pharmaphorum.com
On Feb 3, 2021
@pharmaphorum shared
CRISPR-Cas9 gene editing technology is part of a growing list of new drug applications for cell therapy treatments. Dr Jennifer Harbottle explores how the field is moving forward #pharma #CRISPR https://t.co/qVlqSwMIZb
Open

Casting aside CRISPR scissors and making a point with base editors

Casting aside CRISPR scissors and making a point with base editors

Dr Jennifer Harbottle, senior scientist in the R&D Base Editing team of PerkinElmer’s Horizon Discovery business looks at progress made in CRISPR-Cas9 gene editing.

CRISPR-engineered T cells in patients with refractory cancer

CRISPR-engineered T cells in patients with refractory cancer

CRISPR-Cas9 gene editing provides a powerful tool to enhance the natural ability of human T cells to fight cancer. We report a first-in-human phase I clinical trial to test the safety and ...

Precision Genome Editing Enters the Modern Era

Precision Genome Editing Enters the Modern Era

CRISPR has sparked a renaissance in genome editing. Now, next-generation CRISPR technologies let scientists modify the genome more efficiently and precisely than before. Such tools could ...

Gene-Editing ‘Scissor’ Tool May Also be a ‘Dimmer Switch’

Gene-Editing ‘Scissor’ Tool May Also be a ‘Dimmer Switch’

CRISPR technology shown to ‘dial down’ gene activity in bacteria

You had questions for David Liu about CRISPR, prime editing, and advice to young scientists. He has answers

You had questions for David Liu about CRISPR, prime editing, and advice to young scientists. He has answers

Liu is a co-inventor of "prime editing," which can delete long lengths of disease-causing DNA or insert DNA to repair dangerous mutations.

CRISPR Jump-Starts Gene Therapy

CRISPR Jump-Starts Gene Therapy

Not only is CRISPR restarting gene therapy, it is also establishing a virtuous cycle of technological development.

The newest gene editor radically improves on CRISPR

The newest gene editor radically improves on CRISPR

Researchers have developed “prime editing,” a true search-and-replace function for DNA.

Building better base editors

Building better base editors

New CRISPR base editors make fewer off-target edits and can access more locations on the genome than earlier versions.

Gene-editing tool CRISPR wins the chemistry Nobel

Gene-editing tool CRISPR wins the chemistry Nobel

A gene-editing tool developed just eight years ago that has “revolutionized the life sciences” nabbed the 2020 Nobel Prize in chemistry.

Genome editing with the CRISPR‐Cas system: an art, ethics and global regulatory perspective

Genome editing with the CRISPR‐Cas system: an art, ethics and global regulatory perspective

Over the last three decades, the development of new genome editing techniques, such as ODM, TALENs, ZFNs and the CRISPR‐Cas system, has led to significant progress in the field of plant and ...

CRISPR gene editing explained: What is it and how does it work?

CRISPR gene editing explained: What is it and how does it work?

Everything you need to know about the gene-editing breakthrough that one day could cure disease, eradicate species and build designer babies.

Cutting-edge CRISPR gene editing appears safe in three cancer patients

Cutting-edge CRISPR gene editing appears safe in three cancer patients

The gravely ill patients received altered versions of their own immune cells in an early test

With Rare Speed, Gene Editing Emerges as Biotech’s New Cutting Edge

With Rare Speed, Gene Editing Emerges as Biotech’s New Cutting Edge

Stocks of start-ups wielding tools like Crispr-Cas9 that allow companies to edit DNA and attack genetic diseases and cancer are suddenly hot. But the science is moving with incredible speed ...